I am a PhD student, and i am using c elegans as a model of Machado Joseph Disease to study neurodegeneration. To further characterizw my model
I would like to test the cell death in specific neurons. I was thinking about to cross my model with ced-3 to study apoptosis and with mec-4 to study
necrosis. I was also thinking of performing TUNEL assay in C. elegans. I would like to know if someone know other mutants that work better and if someone
has experience with a TUNEL kit that works good!!
Thanks in advance!