A Research Fellowship for licensed Clinician Scientists is available in the Kraemer lab located at the University of Washington and VA Puget Sound Health Care System in Seattle, WA (see http://depts.washington.edu/mcb/users/kraemerb). We use C. elegans to model and test neuroprotective strategies for the neurodegeneration seen in Alzheimer’s disease, amyotrophic lateral sclerosis, and other aging related disorders.
We are seeking a motivated clinician who wishes to hone their scientific research skills in the context of a collaborative research team. The ability to design, conduct, and report on research experiments is required. Communication skills, organizational skills, and a willingness to learn new approaches are of paramount importance. The fellow will pursue the development of novel neuroprotective strategies targeting the underlying causes of aging associated protein aggregation in neurodegenerative disease using transgenic C. elegans models. We also focus on traumatic brain injury and the resulting neuropathologies including tau and TDP-43 proteinopathy.
Duties and Responsibilities include:
• Small molecule and forward genetic screening for modifiers of neurodegeneration
• Effective communication with internal and external researchers
• Written and oral reporting of research findings
Knowledge/ Skills necessary
• Strong problem solving skills
• Knowledge of genetics, neurology, psychiatry, neurobiology and/or neuropharmacology
• Ability to design and execute controlled experiments
• Aptitude for effective scientific writing
Desirable Experience/Skills
• Knowledge of pharmacology and/or medicinal chemistry
• Experience working with C. elegans
• Competence in microbiology and molecular cloning
• Expertise in studying protein aggregation
• Knowledge of bioinformatics analysis
• Familiarity with transgenic and/or knockout mice
• Experience with cell culture.
Requirements: An MD, current unrestricted U.S. medical licensure, and completion of related ACGME accredited specialty/subspecialty residency training.
To inquire about this opportunity, please respond to kraemerb@uw.edu and attach a single PDF containing a succinct statement summarizing your previous research experience, future research goals, and your CV.