# Disease Pages at SGD: Linking Yeast Genetics and Human Disease

**URL:** <https://community.alliancegenome.org/t/disease-pages-at-sgd-linking-yeast-genetics-and-human-disease/7387>\
**Category:** Tutorials, Information, Help\
**Created:** [December 8, 2023, 11:05pm UTC](https://community.alliancegenome.org/t/disease-pages-at-sgd-linking-yeast-genetics-and-human-disease/7387 "2023-12-08T23:05:25Z")\
**Posts on this page:** 1\
**Page:** 1

<div class="post-metadata">

**Author:** ![stacia](https://community.alliancegenome.org/user_avatar/community.alliancegenome.org/stacia/32/424_2.png) [@stacia](https://community.alliancegenome.org/u/stacia)\
**Post date:** [December 8, 2023, 11:05pm UTC](https://community.alliancegenome.org/t/disease-pages-at-sgd-linking-yeast-genetics-and-human-disease/7387/1 "2023-12-08T23:05:25Z")

</div>

To promote the use of yeast for biomedical research, SGD utilizes the [Disease Ontology (DO)](http://www.disease-ontology.org/) to describe human diseases that are associated with yeast homologs. Disease Ontology annotations to yeast genes are available through SGD’s Disease pages. Each page corresponds to a Disease Ontology term, such as [amyotrophic lateral sclerosis](https://www.yeastgenome.org/disease/DOID:332) or [neurodegenerative disease](https://www.yeastgenome.org/disease/DOID:1289), and lists all yeast genes annotated to the term by SGD.

![neurodegenerative_disease](https://community.alliancegenome.org/uploads/default/original/1X/fb62abfb8699f65653ecdd9556cd4fa64632deec.png)  
_Figure 1. SGD’s Disease Ontology page for [neurodegenerative disease](https://www.yeastgenome.org/disease/DOID:1289)_

Yeast genes with one or more human disease associations will also have a Disease page (example: [MIP1](https://www.yeastgenome.org/locus/S000005857/disease)), accessible from its gene page. The Disease page shows all manually curated, high-throughput, and computational disease annotations for the yeast gene. These pages also feature network diagrams that depict shared disease annotations for other yeast genes and their human homologs.

![network_diagram_disease](https://community.alliancegenome.org/uploads/default/original/1X/118ec77ce3e365a4b9e5dab485f0e7232c72cecb.png)  
_Figure 2. Shared disease annotation network for [MIP1](https://www.yeastgenome.org/locus/S000005857/disease)_

For more information, check out SGD’s [Disease Ontology help page](https://sites.google.com/view/yeastgenome-help/function-help/disease-ontology-do). Explore the Disease pages and features, and be sure to let us know if you have any [feedback or questions.](mailto:sgd-helpdesk@lists.stanford.edu)