Hello everyone,
Ask for your help on finding genetic methods specifically activating individual neurons. Thanks a lot!!!
Hello everyone,
Ask for your help on finding genetic methods specifically activating individual neurons. Thanks a lot!!!
Some endogenous receptors have been described that have cell-specific expression and known ligands or stimuli. Other than these, and more generally applicable, the obvious answer is Channelrhodopsin.
I think it’s also possible to use capsaicin receptor and possibly other receptors for chemicals to which C. elegans doesn’t respond, but these might only be appropriate for surface-exposed sensory neurons.
Thank you!