# PAN-GO Functionome: How to use Function Categories

**URL:** <https://community.alliancegenome.org/t/pan-go-functionome-how-to-use-function-categories/8362>\
**Category:** GO\
**Created:** [March 12, 2025, 11:11pm UTC](https://community.alliancegenome.org/t/pan-go-functionome-how-to-use-function-categories/8362 "2025-03-12T23:11:01Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![suzi](https://community.alliancegenome.org/user_avatar/community.alliancegenome.org/suzi/32/606_2.png) [@suzi](https://community.alliancegenome.org/u/suzi)\
**Post date:** [March 12, 2025, 11:11pm UTC](https://community.alliancegenome.org/t/pan-go-functionome-how-to-use-function-categories/8362/1 "2025-03-12T23:11:01Z")

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## PAN-GO Functionome: How to find genes in a selected function category

GO’s brand new PAN-GO Functionome (ICYMI: [GO’s new human gene resource and accompanying Nature paper on the “PAN-GO Functionome”](https://community.alliancegenome.org/t/gos-new-human-gene-resource-and-accompanying-nature-paper-on-the-pan-go-functionome-is-here/8343)), can be used in many different ways. This how-to is about using the Function Category filters to find human genes of interest.

# **In a hurry? Here’s how to use the Function Categories in the PAN-GO Functionome in less than 30 seconds!**

![functionome_howto_subsets](https://community.alliancegenome.org/uploads/default/original/2X/3/31c826802dfa036ace4a20e87d5c7698a104ed1a.gif)

➡ Remember, if you have any questions, comments, or change requests to data in the PAN-GO Functionome, _your feedback is valued!_ [**GO Functionome Feedback Form**](https://docs.google.com/forms/d/e/1FAIpQLScX_caoY-mqsyK5Y6M2bof7EXVG0UY5DhOQ67zBMoAKKlRF4Q/viewform?usp=sharing)

# Detailed guide on using Function Categories to find human genes of interest:

The PAN-GO Functionome is at [https://functionome.geneontology.org](https://functionome.geneontology.org)

 ![PANGOgenefxn02](https://community.alliancegenome.org/uploads/default/original/2X/c/cab9410bcfd8f073f5c8f3d7fc2f4ac9ff8e4138.jpeg)

In the filter to the left of the screen, type in the name of the functional category. Only terms in the list of Function Categories will be available.

 ![fc01](https://community.alliancegenome.org/uploads/default/original/2X/f/f6fa128f76308888d694a06ab867f3e52edf54cf.jpeg)

If you don’t know the exact name of the Functional Category, you can browse the options below the text box. Each category is color-coded by aspect (Molecular Function, Biological Process, or Cellular Component), and each term has a count of the genes in that category.

Click one or more Functional Categories to add it to the filter. Remove terms by clicking the small X at the top of the panel.

 ![fc03](https://community.alliancegenome.org/uploads/default/original/2X/5/56cc4338474bb6c853601f765a63a8827c284f09.jpeg)

## More about Function Categories (also referred to as GO Subsets, or GO Slims):

The PAN-GO Functional Categories is the list of terms in the GO Generic Slim, [available for download on the GO Subsets page](https://geneontology.org/docs/go-subset-guide/). This list of terms is intended to provide a summary of the ontology without all the detail in the full list of GO terms.

Selection of a Function Category term will include all genes annotated to that specific GO Term, and will also include genes annotated to child terms of that GO term. The Functional Category _chromosome_ will contain [HP1BP3](https://functionome.geneontology.org/gene/UniProtKB:Q5SSJ5), annotated to _chromosome_. That category will also contain [BRDT](https://functionome.geneontology.org/gene/UniProtKB:Q58F21) as it is annotated to _chromatin_. It should exclude the gene [ADIPOR1](https://functionome.geneontology.org/gene/UniProtKB:Q96A54), only annotated to _plasma membrane_, as well as any other genes not annotated to the chosen Functional Categories or the child terms of that term.

[More info available on GO’s Subsets documentation](https://geneontology.org/docs/go-subset-guide/).
