Postdoc in the Biology of Aging and Metabolism at the University of Pittsburgh

A postdoctoral position is available in the Ghazi lab at the University of Pittsburgh School of Medicine to study the genetics of aging and metabolism in C. elegans.
We employ molecular genetics, genomics and biochemical approaches to understand how signals from the reproductive system modulate lipid homeostasis and how this alters length and quality of life. The selected candidate will expand on our recent studies demonstrating the enhancement of lipid production and breakdown in response to germline perturbation (Amrit et al., PLoS Gen. 2016; Ratnappan et al., PLoS Gen. 2014).

We are looking for a highly motivated recent Ph. D graduate with molecular-genetic training in aging, lipid biology or reproduction. Background in model organism research will be greatly valued, but is not essential. The successful candidate will work on a multi-disciplinary, collaborative project to study the role of lipid turnover in aging, employing tissue-specific and whole-animal RNA-Seq, ChIP-Seq, in vivo biomolecular imaging and classical genetics. We are seeking an innovative-thinker and enthusiastic individual who will function well in a collaborative, collegial and lively lab environment. An aptitude for exploration and tackling challenging problems is highly desirable.

The Ghazi lab is located in the Rangos Research Center, a vibrant complex of multi-disciplinary basic, translational and clinical research in the Children’s Hospital of Pittsburgh. The University of Pittsburgh is home to an extensive and rapidly expanding aging community from both research (UPMC Aging Institute and Stimulating Pittsburgh Research in Geroscience initiative) and clinical (Long-Life Family Study center) perspectives. Pittsburgh offers exceptional quality-of-life measures including low cost of living in a lovely, green city gaining national and international recognition for dynamic cultural and culinary scenes (

Interested candidates can email their resume to along names of three referees and a cover letter detailing research experience and future goals.