I am interested to know if anyone has ever done a BSO treatment (buthionine sulfoximine, an inhibitor of g-glutamylcysteine synthetase, the enzyme that synthesizes GSH) in C. elegans.
I would like to know for which doses BSO is lethal or deleterious to worms
PLease contact my student Nando at firstname.lastname@example.org
HE might have performed a pilot experiment on BSO treatment.
Nevertheless, we have not done this experiment in a controlled careful manner so I will very much appreciate if you could please keep me posted on any approach in this direction you might take.
Certainly, we will try to optimize the protocol but we are in the process of moving the lab and have limited resources right now.
Please keep in touch
ALl the best