The Wyss Institute of Harvard University and the Department of Biology at the University of Virginia seek outstanding applicants for two interdisciplinary Research Associates sponsored by the W. M. Keck Foundation to serve as “Keck postdoctoral fellows” in functional genomics and 3D systems biology. The candidates will lead the development of new technologies to create the first single-cell resolution model of animal metabolism using Caenorhabditis elegans.
In the last 25 years, genomic tools have dramatically accelerated the pace of data generation. However, our understanding of how biological systems work has not grown nearly as fast. This project aims to develop and integrate C. elegans functional genomics, in animal RNAseq (FISSEQ), and whole animal modeling tools to develop the first single-cell resolution model of animal metabolism. There are currently no models that can fully represent animal life with its complex levels of organization, from genes, to cells, to organs. Without such models it is not possible to completely anticipate the effects of drugs on different organ systems, to design tissues or organs our bodies would not reject, or simply to understand life at the molecular level. Through the generous support of the Keck Foundation and the PEW Charitable Trust, and your leadership, we will open new doors in biology and biomedicine.
Specific goals include developing FISSEQ in whole C. elegans or optimizing and performing high-content genome-wide reverse genetics screens for fat regulators.
The candidate must have an extraordinary motivation to learn and succeed as an independent scientist. A PhD in biology, chemistry or related experimental sciences by the appointment start date is required. One or more years of experience in molecular biology, cell biology, biochemistry or related lab experience at PhD level is required. Productivity documented with peer-reviewed first author publications is required. Effective oral and written communication skills are required. Experience in at least one of the following is preferred but not required: C. elegans research and/or RNAseq (both library construction and data analysis), high-end microscopy (high-resolution or high-throughput) and/or bioinformatics and biological scripting languages (Matlab, Python/Biopython). No previous post-doctoral experience is preferred. The candidate may be based in the Charlottesville, VA or the Boston, MA areas, but may need to occasionally travel between Charlottesville, VA and Boston, MA.
Apply through Jobs@Uva (https://jobs.virginia.edu). Search for posting number 0619666. Attach: a one-page cover letter describing your scientific accomplishments and your interests, curriculum vitae, and contact information (including phone numbers) of three references who might be contacted for recommendations.
Review of applications will begin November 3, 2016; however, the position will remain open until filled. Questions regarding the research should be directed to: Eyleen O’Rourke ejo8b@Virginia.edu. Questions about the application process or Jobs@UVA should be directed to: Rich Haverstrom rkh6j@virginia.edu
The University will perform background checks on all new hires prior to making a final offer of employment.
The University of Virginia is an equal opportunity and affirmative action employer. Women, minorities, veterans, and persons with disabilities are encouraged to apply.