Alliance Version 6.0 was released on September 29, 2023

The 6.0.0 release adds new features to gene pages:

  • The 6.0.0 release adds a new Paralogy section to Gene pages. Similar to Orthology, the Paralogy data are sourced from the DRSC's DIOPT tool. Each table is ranked based on similarity, identity, alignment length, and a count of algorithms (methods) used to predict a paralogous match. See human HSPA1A gene page for an example.
  • Another new section for gene pages is the Sequence Detail. For different transcripts of the gene, you can choose to view the sequence for the gene, or its CDS, cDNA, protein, gene with collapsed introns, or genomic sequence with or without 500 bp up and downstream.
  • Gene pages' Disease section has several new updates:
    • This section adds new column, Disease Qualifier. The qualifier describes whether a gene may be, for example, a marker for the onset of a disease, or implicated in the severity of a disease.
    • The "Annotation details" pop-up for individual table rows has expanded to include much more information. New columns and information include Association, Additional Implicated Genes, Genetic Modifiers, Strain Background, Genetic Sex, Notes, and Annotation Type.
    • The Download file from the gene page disease table now includes additional information as well. New columns and information include Additional Implicated Gene ID, Additional Implicated Gene Symbol, Gene Association, Genetic Entity Association, Disease Qualifier, Evidence Code Abbreviation, Experimental Conditions, Genetic Modifier Relation, Genetic Modifier IDs, Genetic Modifier Names, Strain Background ID, Strain Background Name, Genetic Sex, Notes, Annotation Type, and Source URL.
    • The Source column entries now link back to their respective resource webpages.
    • The annotations for the gene and species of focus (i.e. whose page you are viewing) are now displayed by default at the top of the table above any other species' disease annotations.