GO and Hagfish

Yu et al. have a new publication in Nature Ecology & Evolution that uses the hagfish to investigate whole-genome duplication in the ancestral vertebrate genome.

Gene Ontology (GO) enrichment analyses demonstrate that the origin of vertebrates was characterized by the appearance of genes involved in signalling pathways, cell communication and transcriptional regulation (Supplementary Tables 24 and 25), while novel core genes involved in immunity played an important role in the origin of gnathostomes (Supplementary Tables 24 and 26).

The paper also uses PANTHER to assign GO terms to human protein sequences. Find more about the PANTHER knowledgebase here.

Find the whole paper here.