In a new open access Nature Communications publication, Tang et al. examine the effects of post-translational modifications on the binding of CCCTC-binding factor and the resulting chromatin structure changes. Tang et al. looked at genes with enhanced peaks on their promoters, and looked at the GO associated with these genes. They found strong correlation with developmental process GO terms:
To read more about the role of PTMs for the 3D chromatin structure, find the article here: The PTM profiling of CTCF reveals the regulation of 3D chromatin structure by O-GlcNAcylation.