Here’s a great new paper that’s notable for a few reasons. Öling et al. have published “A human stomach cell type transcriptome atlas”, where they share their genome-wide cell type-enriched transcriptome atlas. Starting with RNAseq data, they used several tools- including GO- to develop their roadmap of stomach biology. Here’s a portion of Fig 2, which shows over-represented GO terms among genes predicted to be gastric enteroendocrine cell, parietal cell, or gastric mucous cell enriched:
The second fantastic thing about this paper is the citation of the GO knowledgebase, including the PANTHER publication and the GO release version. The addition of this information is invaluable to anyone trying to reproduce, evaluate, or otherwise investigate the transcriptome atlas that has emerged from this publication:
Congratulations to Öling et al. on this great publication that will hopefully help others investigating stomach biology and human diseases. Find the open access BMC Biology paper here.