Here’s an interesting new paper we found: Mahajan et al. have developed their own knowledgebase and tool to conduct GO over-representation analysis for a metabolite list: IDSL.GOA. Although the GO is intended to describe gene function, this is a great example of other ways GO might be used. We have not had a chance to test it out, but if you’re interested they have an online tool: the IDSL.GOA online tool is a user-friendly resource for identifying overrepresented metabolic processes in a list of metabolites. The online interface offers features including analysis, query, explore, statistic and download options. Note this is not an official GO tool and is not affiliated with GO or GOA, please contact the tool developers with any questions about IDSL.GOA.
Find the paper in Scientific Reports.