Important: File URLs and Names Have Changed in 2026-06-19
If you use automated pipelines or scripts that download GO annotation files, your code needs to update by July 2026.
What Changed
- File organization: Annotation files are now organized into
/gaf,/gpad, and/gpisubdirectories - File naming: Files now use UniProt species identification codes (e.g.,
HUMAN-uniprot.gaf.gzinstead ofgoa_human.gaf.gz) - File splitting: Multi-species files (Xenbase, CGD) are now split into separate single-species files
- Two versions for MODs: Both MOD-centric (
DROME-mod.gaf.gz) and UniProt-centric (DROME-uniprot.gaf.gz) versions available
Example changes:
- Old:
https://current.geneontology.org/annotations/goa_human.gaf.gz - New:
https://current.geneontology.org/annotations/gaf/HUMAN-uniprot.gaf.gz
Find Your New File URLs
Complete mapping table: pipeline-from-goa/docs/annotations-mapping.md at main · geneontology/pipeline-from-goa · GitHub
Timeline
- Now-July: Old files available at current locations
- July-September: Old URLs will redirect (when possible)
- After September: Old URLs will no longer work
2026-06-19 Release Statistics
| Metric | Count |
|---|---|
| GO Terms | 38,263 |
| Annotations | 14,736,040 |
| Gene Products | 1,750,636 |
| Species | 171 |
Detailed Release Information
Release statistics: Directory index for http://release.geneontology.org/2026-06-19/release_stats
Ontology changes: https://release.geneontology.org/2026-06-19/release_stats/go-ontology-changes.tsv
Annotation changes: https://release.geneontology.org/2026-06-19/release_stats/go-annotation-changes.tsv
Quick Access
- Current Release: https://current.geneontology.org
- DOI: Gene Ontology Data Archive | Zenodo
- Full Details: Directory index for http://release.geneontology.org/2026-06-19/
Need Help?
help@geneontology.org
GitHub - geneontology/helpdesk: The Gene Ontology Helpdesk · GitHub
https://help.geneontology.org
This change was announced in May and June. We know breaking changes are disruptive - please reach out if you need assistance with the migration.