Would you like to see the shape of your protein?
SGD contains links to AlphaFold in the Resources section of the Summary, Protein and Homology pages for every gene.
- The links through SGD give quick access to EMBL-European Bioinformatics Institute‘s new, highly accurate tool for predicting protein structure.
- Given a peptide sequence for an uncharacterized protein, AlphaFold models predicted domains and provides relative confidence levels for each portion of the prediction.
- The predicted domains can then be compared to known protein structures (using a tool such as PDBeFold to seek matches to characterized protein families).
- Whether or not a family is identified, the comparison will yield clues to protein function to help design your next experiment.