Mutant with enhanced mosaicism?

Model Organism: Worms Scientific Discussion
1

Hi everybody,

I am looking for a mutant that shows enhanced mosaicism of extrachromosomal arrays. Does anyone know of any?

Thanks!

K

2

You could try a background with enhanced nondisjunction, and walk the line between aneuploid lethality and increased mosaicism. I remember somewhere that the him-5(e1490) background is more difficult to get injected lines from. Maybe it also has increased mosaicism? Just a thought. him-5 is mostly X nondisjunction but does impact autosomes somewhat.