Cell Genomics | Jan 10, 2024 | Vol. 4, Iss. 1
Andreas Tsouris, Gauthier Brach, Joseph Schacherer, Jing Hou
Tsouris et al. generated a large diallel hybrid panel using diverse natural yeast isolates and explored the gene expression variation across this population. They showed that the transcriptome is globally buffered at the genetic level, mainly due to genomic variants that act distantly (i.e., in trans) to the expression traits.