An NIH-funded postdoctoral position is available in the Ghazi lab at the University of Pittsburgh School of Medicine to study genes at the intersection of aging, immunity and metabolism.
Our lab investigates (i) molecular mechanisms linking lifespan to aspects of healthspan such as immunity, and (ii) impact of reproductive status on longevity and healthspan, using molecular genetics, genomics and systems approaches in C. elegans. We demonstrated that lifespan and healthspan can be genetically uncoupled and lifespan-enhancing genes may not inevitably improve immunity/healthspan (Amrit et al., Nature Communications, 2019, Naim et al., Aging Cell, 2021). Our recent work has revealed a conserved role for mRNA splicing of lipid-hydrolyzing factors during immune response and aging. The selected candidate will work on a multi-disciplinary, collaborative project to decipher the mechanisms underlying this discovery in C. elegans and mammalian models.
We are seeking an enthusiastic scientist with Ph. D training in aging and/or splicing and/or immunity, who functions well in a lively, collaborative lab environment. Background in model organisms will be greatly valued but is not essential.
The University of Pittsburgh is a leader in basic, translational and clinical research in the fields of aging, metabolism and immunity. Pittsburgh offers exceptional quality-of-life with low cost of living in a lovely, green city recognized for its dynamic tech, culture and culinary scenes.
Interested candidates can email their resume with names of three referees and a cover letter detailing research experience and future goals to ghazia@pitt.edu.