Opportunities for Postdocs, PhD students and Research Assistants.
Gartner Lab - Institute of Basic Science (IBS), Center for Genome Integrity (CGI), Ulsan, South Korea.
In 2020, the Gartner lab relocated from Dundee, Scotland to Ulsan, South Korea in the Institute of Basic Science, Center for Genome Integrity (IBS-CGI) at the Ulsan National Institute of Science and Technology (UNIST) campus.
With UNIST aiming to be among the top Science Universities in the world and IBS having provided a transformative boost to basic research in Korea, we offer a top-notch research environment. The IBS-CGI has access to most generous core support and our ambition at the CGI is to become an internationally leading research center for genome integrity and chromosome biology. The campus is beautifully located in the outskirts of Ulsan, a city of ~ one million surrounded by woods, with excellent connections to all of South Korea by high-speed train. The working language at IBS-CGI is English.
The Gartner lab has a track record focused on understanding basic aspects of genome maintenance, germ cell apoptosis and meiotic recombination using the nematode Caenorhabditis elegans as a model organism. In parallel, we have started to work with mammalian cell culture. We currently have two main C. elegans projects:
(1) Faithful genome maintenance requires all physical connections between chromatids to be removed before the cell divides, in order to prevent aneuploidy or severing of chromosomes due to cytokinesis failure. We recently identified the LEM-3 nuclease (ortholog of Ankle1 in mammalian cells) as part of ‘a last chance mechanism’ that processes DNA bridges between chromatids just before the cell divides (DOI: 10.1038/s41467-018-03135-w). Building up on this work, we are investigating the mechanism by which LEM-3 acts and we are studying this process in more detail.
(2) In parallel, we are studying the pathways leading to DNA damage dependent apoptosis induction in the C. elegans germ line as well as the transcriptional responses resulting from the exposure to ionizing irradiation.
In both projects, we are using a combination of genetic, biochemical and cell biological approaches as well as state of the art equipment (COPAS Wormsorter, Spinning Disc Microscope with temperature-controlled stage and 4D Microscope for C. elegans developmental cell lineaging).
We are looking for researchers with expertise in genetics, molecular and cell biology. Candidates with a recent MS or Ph.D. are particularly invited to apply. For detailed information please have a look at our website.
How to apply: Candidates should submit a letter of interest, curriculum vitae, and the names of three references in a single pdf file to srolland@ibs.re.kr by April 20th, 2022.