A postdoctoral position is available in the Blackwell lab at the Joslin Diabetes Center and Harvard Medical School. Projects are focused around various aspects of how growth, nutrient, and proliferative signals influence stress defense networks and aging in C. elegans.
Recent publications include:
- Tullet JMA, Hertweck M, An JH, Baker J, Hwang JY, Liu S, Oliveira RP, Baumeister R, Blackwell TK. (2008) Direct inhibition of the longevity promoting factor SKN-1 by insulin-like signaling in C. elegans. Cell, 132, 1025-1038. (Featured in a Cell Leading Edge Preview: Cell 2008;132:915-6, Science Signaling as an Editor’s Choice: Sci Signal. 2008;1:209, and Aging Cell 2008;7:605-8). PMID: 18358814.
- Oliveira RP, Porter Abate J, Dilks K, Landis J, Ashraf J, Murphy CT, Blackwell TK. (2009) Condition adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf. Aging Cell, 8, 524-541. PMID: 19575768.
- Wang J, Robida-Stubbs S, Tullet JMA, Rual JF, Vidal M, Blackwell TK. (2010) RNAi screening implicates a SKN-1-dependent transcriptional response in stress resistance and longevity deriving from translation inhibition. PLoS Genetics, 6, pii: e1001048. PMID: 20700440.
- Li X, Matilainen O, Jin C, Glover-Cutter C, Holmberg CI, Blackwell TK. (2011) Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity. PLoS Genetics, 7, pii; e1002119. PMID: 21695230.
- Robida-Stubbs S, Glover-Cutter C, Lamming DW, Mizunuma M, Narasimhan SD, Neumann-Haefelin E, Sabatini DM, Blackwell TK. (2012) TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO. Cell Metabolism, 15, 713-724. PMID: 22560223.
- Mori MA, Raghavan P, Thomou T, Boucher J, Robida-Stubbs S, Macotela Y, Russell SJ, Kirkland JL, Blackwell TK, Kahn CR. (2012) Role of microRNA processing in adipose tissue in stress defense and longevity. Cell Metabolism, 16, 336-347. (Featured in a Cell Metabolism Preview: Cell Metabolism 2012;16:285-286). PMID: 22958919.
- Paek J, Lo J, Narasimhan SD, Nguyen T, Glover-Cutter K, Robida-Stubbs S, Suzuki T, Yamamoto M, Blackwell TK, Curran SP. (2012) Mitochondrial SKN-1/Nrf mediates a conserved starvation response. Cell Metabolism, 16, 526-537. PMID: 23040073.
The Blackwell lab and Joslin Diabetes Center are located in Boston’s Longwood Medical Area, a vibrant research community that includes Harvard Medical School and several large hospitals and research institutions. We have close ties with the Boston C. elegans, aging, and metabolism communities, making this an unusually rich scientific and collaborative environment.
Please apply by sending a cover letter and CV to email@example.com, and by having three letters of reference sent separately.