Postdoctoral positions, Grishok Lab, Columbia University Medical Center, NYC
Two postdoctoral positions are available in the lab of Alla Grishok at Columbia University Medical Center.
The research in the lab is focused on understanding how RNAi connects to transcriptional regulation of genes and what biological roles this regulation might have. Our recent results suggest that some proteins required for RNAi-induced transcriptional silencing (TGS) have a role in positioning nucleosomes and might interfere with transcriptional elongation. Therefore, the goal of one of the projects will be to study the molecular mechanism of TGS in C. elegans. Another interest in the lab includes biological roles of RNAi-induced transcriptional silencing. Recently found connections of endogenous siRNAi pathway to stress response and longevity will be in the focus of this project.
Motivated applicants interested in studying novel phenomena are encouraged to apply. Prior experience with C. elegans and knowledge of protein expression techniques is advantageous but not required.
Please send a letter stating your scientific interests, CV and contact information for 2-3 references to Alla Grishok at ag2691 at columbia.edu