Research & Development Scientist, Rare Disease

We are seeking a creative and highly motivated Scientist with a strong background in molecular biology, genetics and mouse physiology to join our Research & Development team to participate in the development of new and innovative resources. This laboratory-based position will lead a team to conduct research around new and existing mouse models across a number of therapeutic areas, with an emphasis on Rare Disease. He/She/They will interact with the Rare Disease Translational Center leadership and will be expected to manage and mentor research assistants/technicians to facilitate the development and implementation of innovative technologies, and to develop and establish genetic resource initiatives supporting the JAX mission.

The Rare Disease Translational Center supports the overall mission of The Jackson Laboratory: To discover precise genomic solution for disease and empower the global biomedical community in the shared quest to improve human health. The Center works directly with foundations and their associated teams of basic and clinical researchers to generate custom mouse models with clinical mutations to treat and cure rare disease. This position is an exciting opportunity to work directly with the Center in supporting this mission.

Key Responsibilities:

  • Hands-on development of clinically relevant molecular biology and biomarker analysis technologies in key therapeutic areas, with an emphasis on rare diseases.
  • Support characterization and validation of new and existing mouse models to increase their utility to the scientific community.
  • Support collaborative opportunities for new resource development with both internal and external scientists and organizations.
  • Manage a multi-project portfolio, publish key results, manage budgets and provide progress reports. Attend scientific meetings when needed.
  • Direct management responsibilities for a team Research Assistants and Molecular Biology Specialists


  • Ph.D. in Genetics, Biochemistry, Molecular Biology or related field, and extensive experience in mouse physiology and working with mice. An understanding of transgenic and genome editing technologies preferred.
  • Demonstrated ability to lead, direct, train and mentor teams required
  • Positive attitude and professional manner in all interactions; demonstrated commitment to continuous learning and professional development
  • Demonstrated ability to support staff to thrive on change and keep pace with a fast paced, dynamic work environment which is externally focused
  • Evidence of strong scientific productivity that would be demonstrated by publication in high-quality peer-reviewed journals.
  • Ability to work with people across departments and gain their cooperation and commitment to projects with demanding deadlines
  • Excellent written and oral communication skills
  • Excellent organizational skills to track multiple inputs and maintain current drafts, arrange appropriate reviews, bring project to close in a timely manner to meet deadlines.