Stress induced analgesia

Model Organism: Worms Scientific Discussion
1

I have a question to people who are well acquainted with nociception in the worm. Does anyone know about stress-induced analgesia in C. elegans? My search did not turn up anything useful.

2

Hi,

not really a member of the well aquainted group you speak of, but I suppose thermal avoidance has been posited as a model of noiception in the worm:

http://www.pnas.org/content/96/18/10477

This, taken together with research showing that opiate receptors might be important in regulation of the thermal avoidance response:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881580/

provides a starting point. The question of whether worms (can perhaps) show stress-induced adaption to noiceptive cues such as extreme temperatures is alluded to in the Baumeister paper above.

Steve