The December updates to FlyBase Papers with Technical Advances are available

You can find the new papers here: FlyBase:Papers with technical advances - FlyBase Wiki

Unique tau- and synuclein-dependent metabolic reprogramming in neurons distinct from normal aging. (Aging Cell)

We generated metabolomics datasets from the heads of aged flies as well as from the Drosophila models of Parkinson’s disease and Alzheimer’s disease.

Feeding a rich diet supplemented with the translation inhibitor cycloheximide decreases lifespan and ovary size in Drosophila. (Biol. Open)

We developed a chemical/drug feeding method, which is nutrient-rich to avoid additional stress due to poor diet that has normally been used for drug feeding to flies.

Network modulation at stable states. (Phys. Rev. E)

The paper provides a new modeling approach to understanding the behavior of gene networks and designing an approach to controlling network movement from one stable state to another.

Systemic and local lipid adaptations underlie regeneration in Drosophila melanogaster and Ambystoma mexicanum. (NPJ Regen Med)

lipid free food in regeneration lipid mass spectrometry data of regenerating mated females

Studying C9orf72 dipeptide repeat polypeptide aggregation using an analytical ultracentrifuge equipped with fluorescence detection. (Anal. Biochem.)

Use of analytical ultracentrifuge with fluorescence detection to measure protein aggregation in situ

A fast in situ hybridization chain reaction method in Drosophila embryos and ovaries. (Fly)

The reported method, which utilizes modified hybridization and amplification reagents, reduced the RNA staining time for the in situ hybridization chain reaction from 3 days to 1 day in Drosophila embryos and ovaries.

A conserved bacterial genetic basis for commensal-host specificity. (Science)

Live imaging and tracking of individual bacterial cells in the gut of live Drosophila.

Caspar specifies primordial germ cell count and identity in Drosophila melanogaster. (eLife)

Domain Deletion lines for Caspar generated for pUASp-Caspar(deltaUBA, deltaUBX, deltaUAS, deltaUBX-UAS).