The May updates to the FlyBase Papers with Technical Advances page are up!

The new papers can be found here FlyBase:Papers with technical advances - FlyBase Wiki

ATF4-dependent increase in mitochondrial-endoplasmic reticulum tethering following OPA1 deletion in skeletal muscle. (J. Cell. Physiol.)

We have used the SBF-SEM to visualize the organelle contacts.

Conditional chemoconnectomics (cCCTomics) as a strategy for efficient and conditional targeting of chemical transmission. (eLife)

A transgenic chromatin interaction peptide-fused Cas9 exhibits higher mutagenesis efficiency. Additionally, a collection of UAS-sgRNAs transgenic flies have been shown to be valuable for chromoconnectome gene manipulation.

Refinement of a technique for collecting and evaluating the osmolality of haemolymph from Drosophila larvae. (J. Exp. Biol.)

We established improved methods for collecting hemolymph and evaluating its osmolality more accurately and reproducibly.

A new suite of reporter vectors and a novel landing site survey system to study cis-regulatory elements in diverse insect species. (Sci. Rep.)

We created a suite of new DSCP-based reporter vectors for diverse insect species, leveraging dual compatibility with piggyBac and PhiC31-integration, the 3xP3 universal eye marker, GATEWAY cloning, different colors of reporters and markers, as well as Gal4-UAS binary expression.

Eye proteome of Drosophila melanogaster. (Proteomics)

Resource: Drosophila adult eye proteome

A novel adipose loss-of-function mutant in Drosophila. (Fly)

A new drosophila mutant with a loss of function mutation in the gene adipose. The previously used mutant adp[60] line is no longer available and this line adp[1] can replace it in functional studies as it phenocopies the increased fat storage.

Spatially revealed roles for lncRNAs in Drosophila spermatogenesis, Y chromosome function and evolution. (Nat. Commun.)

This paper references the expression patterns of long non-coding RNAs available on the Fly-FISH database (link to database: https://fly-fish.ccbr.utoronto.ca/)

Embryonic spatiotemporal expression pattern of Folded gastrulation suggests roles in multiple morphogenetic events and regulation by AbdA. (G3 (Bethesda))

It is a new resource

Evolutionary analyses of intrinsically disordered regions reveal widespread signals of conservation. (PLoS Comput. Biol.)

A set of IDR alignments across 33 Drosophila genomes where biochemical features of those IDRs have been scored for conservation using models of trait evolution