What are all the possible uses of GO?

It would be impossible to list all the potential applications of GO, but applications for which GO has already been used include the following:

  • integrating proteomic information from different organisms;
  • assigning functions to protein domains;
  • finding functional similarities in genes that are overexpressed or underexpressed in diseases and as we age;
  • predicting the likelihood that a particular gene is involved in diseases that haven’t yet been mapped to specific genes;
  • analysing groups of genes that are co-expressed during development;
  • developing automated ways of deriving information about gene function from the literature;
  • verifying models of genetic, metabolic and product interaction networks.

For references to these and other studies that have used GO, see the GO and the scientific literature page.