PAN-GO Functionome: A compendium of human gene functions derived from evolutionary modelling
GO’s latest Nature paper announces the release of a brand new resource for gene function descriptions: the PAN-GO Functionome. The PAN-GO Functionome uses large-scale evolutionary models to combine data from other well-studied organisms, resulting in an incredibly accurate and comprehensive resource for the functions of human genes. Analyses performed using the PAN-GO Functionome, available at functionome.geneontology.org, are even more informative than those based only on traditional GO annotations- which have been the gold standard for over 25 years.
Additionally, the PAN-GO Functionome invites and encourages all researchers of any level to provide immediate feedback. If you find a gene that is not annotated but you know of research that describes it, you find errors or omissions in the data, or any other concerns, you can instantly request the data to be amended using the feedback link on the PAN-GO Functionome homepage.
- Find the open-access Nature article here: A compendium of human gene functions derived from evolutionary modelling | Nature
- Try out the PAN-GO Functionome now: https://functionome.geneontology.org/
- Find the official Keck School of Medicine of USC Newsroom press release here